Alexander Astrakhan - 2seventy bio, Oncol Discovery

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论文共 42 篇作者统计合作学者相似作者

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Drug-regulated CD33-targeted CAR T Cells Control AML Using Clinically Optimized Rapamycin Dosing

Jacob Appelbaum,April E. Price,Kaori Oda,Joy Zhang,Wai-Hang Leung,Giacomo Tampella,Dong Xia,Pauline P. L. So, Sarah K. Hilton,Claudya Evandy, Semanti Sarkar,Unja Martin,Anne-Rachel Krostag, Marissa Leonardi,Daniel E. Zak, Rachael Logan, Paula Lewis, Secil Franke-Welch, Njabulo Ngwenyama, Michael Fitzgerald, Niklas Tulberg,Stephanie Rawlings-Rhea,Rebecca A. Gardner,Kyle Jones,Angelica Sanabria,William Crago,John Timmer,Andrew Hollands,Brendan Eckelman,Sanela Bilic, Jim Woodworth,Adam Lamble,Philip D. Gregory,Jordan Jarjour,Mark Pogson,Joshua A. Gustafson,Alexander Astrakhan,Michael C. Jensen

JOURNAL OF CLINICAL INVESTIGATIONno. 9 (2024)

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Targeting Human Plasma Cells Using Small Molecule Regulated BCMA CAR T Cells Eliminates Circulating Antibodies in Humanized Mice

Yuchi Honaker, David Gruber,Chester Jacobs,Rene Yu-Hong Cheng, Shivani Patel, Christopher Zavala Galvan,Iram F. Khan, Kevin Zhou,Karen Sommer,Alexander Astrakhan,Peter J. Cook,Richard G. James,David J. Rawlings

Molecular Therapy (2024)

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Enhanced Anti-AML Potency of DARIC33 by iSynPro-IL-15*: An IL-15 Expression Module Driven by a Tightly Regulated Synthetic Promoter Activated by Antigen Receptor Signaling

Jacob Appelbaum,Claudya Evandy,Kaori Oda, Semanti Sarkar,Giacomo Tampella,April Price,Joy Zhang,Wai-Hang Leung,Pauline So,Alexander Astrakhan,Jordan Jarjour,Michael C. Jensen

MOLECULAR THERAPYno. 4 (2023): 80-81

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First in Human Studies Show Activation of SC-DARIC33, a Rapamycin-Regulated Anti-CD33 CAR T Cell Therapy, in Patients with AML

Jacob Appelbaum,Todd Cooper,Colleen Annesley,Adam Lamble,Stephanie Rhea,Sowmya Pattabhi,Joshua A. Gustafson,April Price, Paula Lewis, Scott Currence,Sumati Sundaram,Alexander Astrakhan,Mark Pogson,Jordan Jarjour,Michael C. Jensen,Rebecca Gardner

MOLECULAR THERAPYno. 5 (2023): 7-7

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Bbt369, a Dual-Targeted and CBLB Gene-Edited Autologous CART Product, Demonstrates Anti-Lymphoma Activity in Preclinical Mouse Models

Michael Certo, Christopher Baldeviano, Sharlene Adams, Martin Asimis,Alexander Astrakhan, Andy Chavkin,Maria L. Cabral, Jimmy Chu, Marie Debrue, Devina Desai, John Evans, Pinky Htun,Amanda Iniguez,Jordan Jarjour, Carl Johnson,Harini Kantamneni,Sema Kurtulus,Michael Magee,Unja Martin,Seamus McKenney, Sara Miller, Prashant Nambiar,Vinh Khang Nguyen,Mauris Nnamani, Jen Obrigewitch,Lisa Pechilis,Molly Perkins,Christopher Petersen, Jason Pinger,Cindy Rogers,Nick Rouillard, Kendal Sanson,Emily Thompson,Collin Walter,Roslyn Yi,Sarah Voytek,Philip Gregory

Cancer Research（2022）

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A Drug-Regulated Anti-Cd33 Chimeric Antigen Receptor With Potent Anti-Aml Activity And A Reversible On-Off Switch

Jacob S. Appelbaum,Unja Martin,Joy Zhang,Kaori Oda,Mark Pogson,Giacomo Tampella,Dong Xia,Anne-Rachel Krostag,April Price,Pauline So, Wei-Hang Leung,Alexander Astrakhan,Jordan Jarjour,Joshua Gustafson,Michael Jensen

MOLECULAR THERAPY（2021）

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Sensitive and Adaptable Pharmacological Control of CAR T Cells Through Extracellular Receptor Dimerization

Wai-Hang Leung,Joel Gay,Unja Martin,Tracy E. Garrett,Holly M. Horton,Michael T. Certo,Bruce R. Blazar,Richard A. Morgan,Philip D. Gregory,Jordan Jarjour,Alexander Astrakhan

JCI INSIGHT（2019）

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A Novel Approach to Targeting NKG2D Ligands Using Engineered T cells Expressing Dimerizing Agent Regulated Immunoreceptor Complexes (DARIC)

Wai-Hang Leung,Unja Martin,Dong Xia,Anne-Rachel Krostag,JayLee Johnson,Jordan Jarjour,Alexander Astrakhan

MOLECULAR THERAPY（2019）

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