Aaron Wheeler's research is focused on the development of lab-on-a-chip techniques for high throughput proteomics and drug discovery. This concept is meant to reduce reagent consumption and analysis time, the capacity to integrate multiple functions onto a single device, and the potential for high throughput analysis. One of the main technologies used in his research is digital microfluidics (or “DMF”). In DMF, discrete fluidic droplets are manipulated on the surface of an array of electrodes coated with a hydrophobic insulator. Currently, Aaron Wheeler is developing methods of microchannels and digital microfluidics for high-throughput bioanalytical applications.