His current research focusses on the development and implementation of metabolomic approaches in cancer epidemiology. Main objectives of his group are to discover novel biomarkers of exposure for dietary, environmental, and other lifestyle factors, and to identify risk factors for cancer and intermediate end-points through biomarker approaches. Robust methodologies developed in his lab for both targeted and untargeted metabolomic analyses have been applied in large multicentric epidemiological studies such as the European Prospective Investigation on Cancer and nutrition (EPIC) study and other EU-funded projects (EXPOsOMICS, TRANSCAN MetaboCCC). He developed the Exposome-Explorer database on biomarkers of exposure to disease risk factors. Before arriving at IARC in 2010, he conducted research at the National Institute of Agriculture Research (INRA) on the structure of lignins and tannins in lignocellulosic materials (INRA Grignon) and on the bioavailability and functions of dietary polyphenols in human nutrition (INRA Clermont-Ferrand). He has been identified as a Highly Cited Researcher (Clarivate Analytics).